El siniestro doctor Orloff borrows the basic story outline of The Awful Dr. Orlof, shifts agency from the infamous surgeon onto his psychotic son, and infuses the mise-en-scène with cut-price retro sci-fi, harking back to Dr. Orloff’s Monster and La venganza del doctor Mabuse. Sadly, as a return to the site of former glories it substantially lacks the charm of its forebears. What emerges is a pale shadow of the classic original, lacking any of its atmospheric seductiveness. … This is a film of missed opportunities and, for a supposed horror project, a lack of interest in terror that borders on contempt. … While it’s marginally better than the talky and tedious Los ojos siniestros del doctor Orloff and at least give us a chance to see Howard Vernon back in the role that made him a horror icon, El siniestro doctor Orloff simply cannot hold a guttering candle to the Orloff films of the 1960s.